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This means the body may need less insulin to keep blood sugar levels in check

It have also demonstrated that under the mediation of metformin, patients have increased Butyrivibrio, Megasphaera and Prevotella levels, promoting the production of SCFAs to alter gut microbiota composition

Franceschini A, Capece M, Chiozzi P, Falzoni S, Sanz JM, Sarti AC, Bonora M, Pinton P, Di Virgilio F (2015) The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein