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Three groups were vaccinated three times at three-week intervals with the following formulations: metE-DNA (100 g/100 L PBS/mouse), MetE protein alone (1 g/100 L PBS/mouse), and 1 g metE protein combined with AddaS03 adjuvant at a 1:1 volume ratio in a total of 100 L PBS/mouse, and AS01 adjuvant (5 g monophosphoryl lipid A [MPL]/5 g QS-21 in a total of 100 L PBS/mouse, representing 1/10th of the human dose of AS01)

Jul 1984;35(7):443-50

Tip: If you experience persistent or severe side effects, consult your healthcare provider immediately to determine if dosage adjustments or alternative treatments are needed