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Antiandrogenic activity of Artemisia herba-alba in male rats, with emphasis on biochemical parameters

(20) Common dosages are (19): 20-40 mg daily for isopropanolic extract 64-128mg daily for aqueous-ethanolic extract taken in divided doses 40-80 daily as a standard recommendation for general black cohosh supplements Black cohosh is likely safe when taken in recommended doses for healthy women

H&E and Safranin-O/Fast green staining demonstrated that the mice in OA group showed disrupted articular cartilage, erosion, extensive proteoglycan loss, and cell reduction, while the ones in sham group maintained regular cartilage morphology (Fig