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Then, all animals were euthanized by bleeding after transection of the abdominal vena cava under anesthesia and the liver, heart, soleus muscle, gastrocnemius muscle, tibialis anterior muscle, extensor digitorum longus muscle, epididymal white adipose tissue, and brown adipose tissue were harvested and immersed in RNAlater solution (Qiagen, Venlo, Netherlands) for qPCR analysis

(97), which has done the optimization of surface charge as a design parameter of paramount importance

As the understanding of copper homeostasis in cancer grows, these nano-delivery platforms possess immense potential to transform cuproptosis from a mechanistic novelty into a clinically viable therapeutic paradigm

For patients suffering from melasma, Dr