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P300/CBP is a broad-spectrum acyltransferase that primarily relies on its conserved HAT domain to recognize and bind acyl-CoA, such as glutaroyl-CoA

This suggests that oxidative glutamate could be a part of an excited viral cascade and may provide a form of cell death that is independent of iGluRs

In contrast to the short-time exposure of exogenous Cys, its long-time exposure significantly induced the expression of CuSOD1 , CuSOD2 , and MnSOD1 in the shoots but did not alter any of the enzymatic antioxidant genes in the roots, suggesting that its role in the shoots is more to scavenge O 2 as a late response

Sahin U, Kariko K, Tureci O