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The main therapeutic goals often include: Enhancing lipolysis , or the breakdown of stored fat

Some of these remedies may show temporary improvement in skin tone, but they also come with inherent risks such as allergic reactions, skin irritation and potential damage to the skin barrier

Blood pressure and heart medications (e.g., lisinopril, metoprolol) for cardiovascular conditions

No tolerance development to the lipolytic effects was noted in these studies, suggesting that unlike beta-2 agonists (which rapidly desensitize their receptors), beta-3 receptor activation may not produce the same downregulation pattern