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Mitochondria-targeted antioxidants, such as MitoQ and SkQ1, can alleviate oxidative stress and reduce tissue damage ( Salmonella infection, thereby preserving mitochondrial function ( Helicobacter pylori -associated gastric pathology, VacA channel blockers offer a promising approach to prevent toxin-mediated mitochondrial disruption ( In addition, the polyphenol epigallocatechin gallate (EGCG) has been shown to suppress cGAS activation, thereby mitigating Carbapenem-resistant Acinetobacter baumannii -induced inflammation and mitochondrial dysfunction, highlighting its potential as a host-directed immunomodulator (Yang et al., 2024)

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Thus, it has been revealed that this plant extract has anti-asthmatic activity, effective against bronchial asthma, allergic asthma, and mild asthma at 375 mg/kg [134, 135]

Cell pellets were resuspended in reducing lysis buffer (20 mM potassium phosphate, 200 mM NaCl, pH 7.4, 10 mM DTT, 0.01 mg ml 1 DNase I) to an OD 600 of 140 and lysed by two rounds of sonication for 2 min at 50% amplitude with 2 s intervals using a Sonopuls (Bandelin) sonicator