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To benchmark our approach against FI and established metabolomic clocks, we constructed comparator models that reflect key elements of prior frameworks trained on age 17 or untransformed metabolite levels 19 , though these models were developed on targeted NMR platforms and focused on age or mortality rather than health decline

[DOI] [PubMed] [Google Scholar] 215.Suzuki A, Yamanaka T, Hirose T, Manabe N, Mizuno K, Shimizu M, Akimoto K, Izumi Y, Ohnishi T, Ohno S

Generally, a GSH content of 35 % could be obtained using strains selected via classical selection strategy, but the exact mechanisms underlying higher GSH accumulation in these mutants has remained rather obscure

Current research focuses on engineering vesicles for targeted drug delivery and metabolic modulation through cargo manipulation