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Anastrazole and oral contraceptives: a novel treatment for endometriosis

MT1-MMP overexpression in mouse liver induces insulin resistance To further investigate whether the upregulation of MT1-MMP impairs insulin action in vivo, we used an adeno-associated viral vector to ectopically express either wild-type MT1-MMP, catalytic inactive MT1-MMP mutant (MT1 EA) or GFP control in the liver