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It targets tumor cells and inhibits tumor progression by reducing the production of 2-hydroxyglutarate (2-HG) mediated by isocitrate dehydrogenase 1 (IDH1mt) (84)

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As a major intracellular reductant, GSH directly scavenges reactive oxygen species and supports enzymatic antioxidant defense pathways such as glutathione peroxidase

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Turrens JF, Boveris A: Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

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4C), while the negative ion mode revealed 178 differential metabolites between the QCHS and DSS groups (Fig

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