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[185] Mounting evidence from postmortem patient tissues suggests a similar gainoffunction of misfolded wildtype SOD1 may contribute to neurodegeneration in sporadic ALS,[ 90b , 165a , 186 ] idiopathic Parkinson's disease, [13] and potentially Alzheimer's disease, [91] although large insoluble misfolded SOD1 deposits are not consistently identified in patient tissues between studies.[ 90a , 90b ] Variation in choice of immunodetection antibodies and methodologies and variation in type and quality of postmortem tissues between research groups likely contributes to the lack of reproducibility of these data

References He N, Zhang Y, Zhang L, et al (2021) Relationship between Sarcopenia and cardiovascular diseases in the elderly: an overview

Macrophages polarize to either M1 macrophages or M2 macrophages, and these phenotypes are dependent on the broader environment that the cells are in [146]

Template synthesized polypyrroles as a carrier for diastase alpha amylase immobilization