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Yan et al., 2017)

Once released, ellagic acid undergoes cleavage of a carbonoxygen bond, resulting in lactone ring opening, followed by a decarboxylation reaction that yields the first urolithin intermediate

a The cryosections were incubated with a specific mouse monoclonal antibody for -tubulin III (red color) in combination with a rabbit polyclonal antibody for S-100 (green) followed by incubation with Alexa Fluor 488- and 594-conjugated secondary antibodies