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In colitis, aberrant activation of the MAPK cascade amplifies the production of pro-inflammatory mediators and cytokines, fostering a state of sustained inflammation and tissue damage

This patient's Parkinson disease motor fluctuations stem from nigrostriatal dopamine depletion, making an adrenal enzyme involved in systemic epinephrine synthesis irrelevant to his required treatment

Pathology 54:104110 Di Martino MT, Leone E, Amodio N, Foresta U, Lionetti M, Pitari MR, Cantafio MEG, Gull A, Conforti F, Morelli E (2012) Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo EvidenceAntitumor Activity of miR-34a in Multiple Myeloma

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