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It leads to nerve damage and neurological issues

AIF plays a dual role in regulating cell survival and apoptosis: its translocation to the nucleus causes caspase-independent apoptosis in response to death stimuli, while in the mitochondria, AIF maintains OXPHOS function via posttranscriptional regulation of respiratory chain complexes through its NADH oxidoreductase activity [31, 32]

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

Mevalonate pathway alterations and targeting in MM Statins are well-known inhibitors of HMGCR as well as of the mevalonate pathway rate-limiting enzymes, which are crucial for cell growth and survival