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When circulating T 4 levels decrease, the pituitary gland increases its secretion of TSH, resulting in increased iodine trapping, as well as increased production and release of both T 3 and T 4

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280 Another study on BCLM showed that the quantification of ctDNA in the participants cerebrospinal fluid achieved a remarkable 100% sensitivity and specificity in diagnosing BCLM, exceeding the traditional gold standard cytology method