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10.1016/j.jchromb.2017.11.039 163 ZhouC.ChenJ.LiuK.MaharajanK.ZhangY.HouL.et al (2023)

By age 60, GHK-Cu levels in the body have fallen by roughly 60% a decline that correlates directly with the visible signs of skin aging: thinning, wrinkling, loss of firmness, slower healing

This restoration of the cellular powerhouses leads to a gradual increase in ATP production

This suggests that patients with alopecia areata may have a stronger reactive oxygen production response, leading to the depletion of metal elements required for enzymatic antioxidants in the body