glutathione increases in cancer cells Involvement of peroxidases the occurrence and development of breast cancers | Journal of Translational Medicine A study shows that the

L-theanine supplementation reversed these changes, suggesting its potential to limit AGEs accumulation and/or promote AGEs clearance

Enrichment analysis was performed using the GSEA software version 4.3.3 (Broad Institute) [33, 34], using gene sets from the Molecular Signatures Database (MSigDB), including the Hallmark, Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology Biological Process (GOBP) collections, and the cultured human stem cell classification Mueller Plurinet [35,36,37,38]

Additionally, while preclinical studies provide valuable insights, the translation of these findings to clinical practice remains challenging due to differences in experimental models, human disease complexity, and pro- and anti-inflammatory properties of 12/15-LOX

L-theanine is not a replacement for medical treatment for anxiety, insomnia, depression, ADHD or high blood pressure, but it may be a helpful supplement for otherwise healthy adults who want support for stress, relaxation, focus or sleep quality