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Our computations show that the sexual dimorphism in one-carbon metabolism plays only a small role in the glutathione pathway (the velocity of CBS is not much different in the two cases, Table 1)

However, the LC 50 value of MSNs-ss-SA was determined to be 1.98 mM, approximately six times greater than that of free SA ( LC 50 = 0.336 mM), indicating a significant reduction in toxicity due to the grafting of SA molecules onto MSNs-ss-NH 2

According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), it can be defined as a neurocognitive disorder/senile dementia with Lewy bodies [101] The histological abnormalities noticed in these people are cortical Lewy bodies