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Notable proteins, such as glial fibrillary acidic protein, brain-derived neurotrophic factor, protein S100B, and neural cell adhesion molecules, have been identified as neuronal markers linked to GBM pathology

Moreover, the results obtained for external test sets prove great generalization capabilities of the developed models, as evidenced by similar values of a (0.9131.002), b (0.0140.121), and R 2 (0.9350.987) in relation to linear fit parameters characterizing train sets (Table 2)

BMC Cancer 16 , 3 (2016)

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