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10.1016/j.redox.2019.101320 128 PedroteM

Aim - Since Zn/Cu superoxide dismutase is increased by about 50% in children with Down syndrome, glutathione and other less known antioxidant mechanisms were studied to determine whether there were changes in reactive oxygen species

Then, the supernatant was removed and the tubes were rinsed with ice-cold acetone containing 0.1% HCl, centrifuged, and rinsed again with 100% ice-cold acetone

Although several strategies based on RMT or AMT pathways have been explored to enhance drug delivery into the brain so far, few of these strategies proved to be noninvasive and effective