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The mixture was heated in a boiling water bath (100 C) for 45 min and then cooled on ice for 30 min

Lockyer S, Yaqoob P, Spencer JPE, Rowland I. Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action. Nutrition and Aging. 2012;1(2):125-140. doi:10.3233/NUA-2012-0011

Activated HSCs express a large amount of -SMA, transform into myofibroblasts, and synthesize ECM that accumulates in the liver to cause fibrous scarring