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Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development

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The glucagon receptor activation becomes measurably active at this level, which can cause a slight increase in heart rate (5-10 bpm) and a warmth sensation as thermogenesis increases