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For example, people who maintain a vegetarian or vegan diet, people with absorption disorders, and those taking prescription meds like Metformin, Proton Pump Inhibitors (PPIs), and H2 blockers like Pepcid are often at greater risk

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Depending on the severity of a patient's functional deficiency or their specific genetic makeup, healthcare providers may recommend starting with a lower dose and gradually titrating up, monitoring for improvements in energy levels and cognitive clarity while keeping an eye out for any temporary over-methylation symptoms, such as mild anxiety or jitteriness