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doi:10.1007/s00213-024-06735-1 Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE

A: Coenzyme Q10 supports heart health by helping the heart muscle produce energy

As further described below, anti-cancer agents encompass biotherapeutic anti-cancer agents (e.g., interferons, cytokines (e.g., tumor necrosis factor, interferon alpha, interferon gamma, etc.), vaccines, hematopoietic growth factors, monoclonal serum therapies, immunostimulants and/or immunomodulators (e.g., IL-1, 2, 4, 6 and/or 12), immune cell growth factors (e.g., GM-CSF), and antibodies (e.g., trastuzumab (trastuzumab), T-DM1, bevacizumab (bevacizumab), cetuximab (cetuximab), panitumumab (panitumumab), rituximab (rituximab), tositumomab (tositumomab), etc.), as well as chemotherapeutic agents

g,h , Representative immunofluorescence of 4T1 ( g ) and MCF10A PIK3CA H1047R ( h ) cell lines overexpressing empty vector or PLGRKT (n = 3 replicates) showing localization of PLGRKT within the mitochondria