It creates a high peak of pain relief and is best suited for acute, severe pain, like the first 24 hours after a tooth extraction, a severe migraine, or right after an injury like a sprain or fracture
In addition, when implanted in rats, they enhanced endometrium regeneration, increased local angiogenesis, encouraged myometrium rejuvenation, and, ultimately, retained fertility (Jin et al., 2023)
Approval for the trials was granted by the Research Ethics Committee of the University of Tartu (270/T-13 and 236/T-10) and the Estonian Agency of Medicines (RKU-4/28 and RKU-4/18) and registered at Clinicaltrials.gov (NCT02089256 and NCT03160261)
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