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10.1101/gad.1723908 Genes Dev

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Scientists are exploring its effects on the following pathways in animals or cells Lipid peroxidation and levels of glutathione, superoxide dismutase (SOD), and catalase [63] Levels of vitamins C & E and DNA damage [81] Gene expression and enzyme interactions (HDACs, HATs, DNMT I and miRNAs) [82] Blood inflammatory markers (IL-8, IL-10, and TNF-) [83] Chronic fatigue and prostate inflammation [84, 85] IL-18 [86], PAI-1 [87, 88] and mTOR [89, 90] Tregs [91, 92, 93] Mast cells [94], DAO, and histamine [95] Cholinergic activity and nicotine binds to (alpha 7-nACh) receptors [96, 97] Cancer Research Neither turmeric nor its active compound curcumin have been shown to treat or prevent cancer

Mut-p53 accumulation sensitizes cancer cells to ROS stress We next examined the consequences of mut-p53 accumulation on cellular redox balance