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Tier placement is based on current health status, not desired speed of results

In contrast, periods with the most positive water balances (centered at 50 CE, 275 CE, 525 CE, and 725 CE) coincide with reduced (1 to 1 C) seasonal temperature gradients, which suggests longer wet seasons in the northeastern Caribbean

While vitamin B12 deficiency is associated with optic neuropathy, its presentation typically involves gradual, painless, bilateral central vision loss due to damage to the optic nerve, and it is rarely associated with the acute, painful onset characteristic of optic neuritis