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Freie Radikale und oxidativer Stress Fr hhere Lebewesen ist es lebensnotwendig, Energie durch das Einatmen und Ausatmen von Sauerstoff zu gewinnen

doi: 10.3389/fneur.2023.1158366 Received 03 February 2023 Accepted 07 March 2023 Published 23 March 2023 Volume 14 - 2023 Edited by Dongsheng Fan, Peking University Third Hospital, China Reviewed by Wenjing Wang, Peking University Third Hospital, China

In LPS-treated BV2 cells and rat primary microglia, UA inhibited the production of pro-inflammatory cytokines (e.g., NO, TNF-, and PGE2) to shield dopaminergic neurons from the toxic effects of activated microglia