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While previous studies have shown that HSP70 and HSP90 are upregulated in response to oxidative stress and play protective roles in maintaining lens transparency [33], the downregulation observed in our HRS-treated model is most parsimoniously interpreted as a consequence of reduced chronic stress signaling, allowing cellular homeostasis to be restored

Metformin targets mitochondrial complex I to lower blood glucose levels

Bariatric surgery Bariatric surgery encompasses a range of surgical interventions designed to induce significant weight loss in individuals with severe obesity, particularly when conventional approaches such as pharmacotherapy and lifestyle modification have proven ineffective

In contrast, reduced copper bioavailability inhibits the proliferation of KRAS mutant tumor cells (90)