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Over 900 subjects participated in clinical trials examining AOD-9604s safety and efficacy, making it one of the more extensively studied peptide fragments in metabolic research

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The eligibility criteria for most FDA-approved weight loss drugs are as follows: Body mass index (BMI) of 30 or higher (classified as obesity) Body mass index (BMI) of 27 or higher (classified as overweight) with one weight-related health condition, such as hypertension, hyperlipidemia, heart disease, and high blood cholesterol levels

It means that as a standalone oral therapy at the tested doses, it did not produce the magnitude of weight loss that pharmaceutical companies require for commercial viability