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Anecdotally, we find TUDCA to be the more efficacious supplement, with milk thistle being a backup option for our patients

Casale GP, Singhal M, Bhattacharya S et al (2001) Detection and quantification of depurinated benzo[a]pyrene-adducted DNA bases in the urine of cigarette smokers and women exposed to household coal smoke

Diet alone does not deliver these compounds in the concentrated, bioavailable form that subcutaneous injection provides

These findings suggest that immune checkpoint inhibitors may provide benefit across a range of disease burden, including bulky tumors considered resistant to other categories of immunotherapy