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225 In addition to its role in metabolism, HIF-1 contributes to GBM invasiveness by promoting EMT through the activation of the Snail and ZEB1 transcription factors, downregulating E-cadherin, and enhancing ECM remodeling

The results of these studies, which were limited to animal models and a small population, can only be considered preliminary and more research are needed to determine the pharmacological effects of Panax ginseng C.A