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Without a delivery technology, topical PDRN is approximately as effective as any aqueous solution applied to a closed barrier

Individuals with Wilson's disease, known metal allergies, or those who are pregnant or breastfeeding should consult a GP or pharmacist before use

These symptoms are often motor abnormalities associated with cerebellar or extrapyramidal injury.26 They may include tremor, coordination defects, dystonia, or choreiform movements.2729 Sensory function and intelligence are generally unaffected in Wilsons disease

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