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In the context of GWS, studies on oxidative stress are limited and its role in GWS remains underexplored (Fukuda et al., 2016)

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23, 24, 25 In the adult kidney, AT 2 receptors are mainly localized in the glomerular mesangial cells 22, 26, 27 or the adventitia of the preglomerular arcuate and interlobular arteries

In this study, we demonstrate that long-term supraphysiological range of OsG/ROS stresses disrupts the FoxO1/TXNIP pathway and results in -cell dedifferentiation, mass loss, and failure

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