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A 2022 study in the Journal of Cosmetic Dermatology found that subjects who applied L-ascorbic acid followed immediately by GHK-Cu experienced 40% higher transepidermal water loss (TEWL) and delayed barrier recovery compared to those who separated application by eight hours or more

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[DOI] [PubMed] [Google Scholar] 48.Van Effenterre G., Ameline B., Campinchi F., Quesnot S., Le Mer Y.J.H

For each skin specimen, two sections were analyzed, and positive cells were counted in four adjacent fields at a magnification of 200X