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3e, f)), increased exopher levels (Supplementary Fig

First, 100 L of methanol containing internal standards (100 M N ,N -diethyl-2-phenylacetamide and d-camphor-10-sulfonic acid) was added to the plasma samples (100 L), and then samples were centrifuged at 14,000 rpm for 5 min

There is substantial evidence showing that HbA1c level is a primary risk factor contributing to the development of small blood vessel (microvascular) complications in patients with type 1 and type 2 diabetes mellitus, a risk that increases exponentially as HbA1c levels rise (Penno 2013)

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