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Misfolded wild type SOD1 is observed in sALS cases and the existing treatments for SOD1-related fALS, such as the antisense oligonucleotide therapy Tofersen, may have a possibility to be applied to these sALS cases (Marlow et al., 2025)

Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes