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doi: 10.1073/pnas.1608264113

psychiatry 25 (11), 29322941

(ii) Human primary cells in vitro Aspartame (0.4410 M) had no effect on the transcriptional activity of the genes encoding the aryl hydrocarbon receptor (AhR) and glucocorticoid receptor (GR), or on AhR-dependent or glucocorticoid receptor-dependent expression of cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) in human primary hepatocytes (Kamenickova et al., 2013)