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S-Acetyl-L-glutathione (50 M) increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency.1 It induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells when used at a concentration of 5 mM

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Thus, protein AMPylation is emerging as a novel signaling mechanism with relevance to diverse pathobiology

Neurosci Lett 596:108