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The incidence of adverse drug reactions (ADRs) was 16.67% in the single-dose groups and 4.17% in the multiple-dose groups, demonstrating the favourable safety and tolerability of SA55 nasal spray in healthy volunteers (Hu et al., 2024)

Persistent or severe headaches warrant medical attention

B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month