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In a review of clinical trials lasting over a year published in The American Journal of Cardiology, adults taking weekly injections lost on average about 12% of their body weight, and about one-third of participants lost 20% or more of their starting weight

Overall, the compliance rate was high, with more than 80% of tablets taken in each trial group

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Research demonstrates that 5-Amino-1MQ exhibits high selectivity for NNMT and does not inhibit structurally related methyltransferases or other enzymes in the NAD+ biosynthesis pathway, including NAMPT and SIRT1