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EGFR The amplification and mutation of EGFR, particularly the EGFRvIII variant, are defining characteristics of GBM, especially in the classical subtype and primary GBM cases

Local SNc injections of wild-type or mutated (e.g., A53T or A30P) syn can lead to efficient transduction of TH-positive neurons in rats with progressive development of LN- and LB-like inclusions, 3080% DA cell loss, 4050% reduction in DA transmission, and reduced motor function [62]

doi: 10.1016/j.mce.2009.09.014 188 VirtueSPetkeviciusKMoreno-NavarreteJMJenkinsBJHartDDaleMet al

doi: 10.3389/fphar.2018.01001 Summary Keywords chronic obstructive pulmonary disease, microbiota, gut-lung axis, prevention and treatment, fecal microbiota transplantation, nutritional therapy Citation Wang Y, Li X and Gao F (2025) Chronic obstructive pulmonary disease: in-depth analysis of microbiota association and innovative prevention and treatment approaches from the gut-lung axis perspective