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During the process, the interaction of iron in heme with the endoperoxide bridge has been confirmed to generate reactive oxygen radicals

2 Role of a healthy endothelium in the regulation of blood pressure 2.1 The endothelial cell layer While until the early 1980s it was believed that the endothelium had a solely passive role in organizing the vascular envelope and managing the selective passage of water and electrolytes alone, it is now known that this tissue performs numerous other vital functions

This dual role makes astrocytes a critical target for research and treatment in PD