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Not a vague brightening promise a documented result

doi: 10.20892/j.issn.2095-3941.2019.0353 102 RaychaudhuriBRaymanPIrelandJKoJRiniBBordenECet al

Our roGFP2 measurements confirm (i) that dynamic roGFP2 sensing (or the physiological glutathionylation/deglutathionylation of regular surface-exposed cysteinyl residues) requires a glutaredoxin activity, and (ii) that glutathionylated proteins or metabolites should be very transient redox species when GSH and glutaredoxins are present (unless they are stabilized by a kinetic uncoupling mechanism) 5,32,34,35,61,62,63,64