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Funding for this work was supported by the Massachusetts General Hospital, Harvard Medical School, Stanford University School of Medicine, UC Davis MIND Institute, and an Autism Center of Excellence grant awarded by the National Institute of Child Health and Development (Grant P50 HD093079)

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Moreover, senescence cells secrete many bioactive molecules collectively termed the senescence-associated secretory phenotype (SASP), which can induce chronic inflammation, alter tissue architecture, and promote tumorigenesis through paracrine signaling