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Liver fibrosis is a key determinant of disease progression, and higher fibrosis stages are associated with an increased risk of liver related complications, including cirrhosis, HCC, and liver failure [45]

Contemporary syntheses quantify the shifting aetiologic mixdeclining viral hepatitis where vaccination/antivirals scale, and rising metabolic liver disease in parallel with obesity, diabetes, and alcoholinforming prevention, surveillance, and workforce planning [431]

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