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doi: 10.1111/j.1365-2443.2008.01252.x

To enhance the immunogenicity of peptide-based cancer vaccines, conjugates and polymers can be used to target peptides to specific immune cells or to include stimulation molecules

Moreover, the provision of IL-15 and IGF-1 to CD34 + cells was associated with upregulated mRNA signals for PRF1 (which encodes perforin), GzmB (which encodes Granzyme B) and IFNG (which encodes interferon- (IFN-)) (Fig