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[DOI] [PubMed] [Google Scholar] 200.Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, et al

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In the SURMOUNT-1 obesity trial, tirzepatide produced mean weight reductions of roughly 1521% depending on dose over 72 weeks ( Jastreboff et al., NEJM 2022

TFR1-mediated iron uptake mainly regulates the growth and development of mature osteoclasts, but its impact on osteoclast precursors is relatively limited (93)