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Analytical SEC Analytical SEC was performed by applying 20 g of each anti-NIP IgG variant to a Superdex 200 Increase 3.2/300 analytical SEC column (Cytiva Lifesciences) at a flow rate of 0.05 mL/min using an AKTA FPLC instrument (Cytiva Life sciences)

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For example, 50 nm silica nanoparticles showed the highest tumor accumulation out of particles sized 20, 50, and 200 nm in a muse primary and metastatic breast cancer model 52 , whereas 30 nm micelles were reported to be optimal for a poorly permeable pancreatic tumor model in mice 46

Wang MJ, Cai WJ, Li N, Ding YJ, Chen Y, Zhu YC