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Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS) is a swiftly advancing, fatal neurodegenerative disorder linked to mitochondrial dysfunction, 288 primarily resulting in the degeneration of motor neurons within the central nervous system (CNS) because of unmet energy demands, leading to muscle weakness and eventually respiratory failure

Rarely, severe cases require liver transplantation

This can be interpreted as either both types of sweet stimuli activate the same pathway, or that two different pathways coexist in the same cell and interact

Phytochemical characterization, antioxidant potential and antibacterial activity of Araucaria columnaris against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes